Prefilled syringes:A solution designed to enhance safety and efficiency in radiology units

Prefilled syringes:
A solution designed to enhance safety and efficiency in radiology units

The use of prefilled syringes for contrast media administration allows efficient and optimized workflow during radiologic diagnostic procedures, and reduces the risk of contamination, providing benefits for both patients and healthcare workers. (1)


Prefilled syringes can bring several benefits to your daily practice

  • Allow time-efficient assembly of injection systems2
  • Help prevent microbiologic contamination in clinical routine, especially in the case of immunocompromised patients2
  • Help on the reduction of crossed-infection or patient administration errors1
  • Reduce healthcare professionals exposition to risks such as broken glass or needles3
  • Offer a sterile and closed system
  • Help on the time management4
  • Allow easy manipulation5

Manual filling of syringes is a possible source of infection amongst healthcare professionals (6,7)

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Dotarem® (Gadoteric acid) in Prefilled Syringes

The first ionic macrocyclic GBCA in the market, available in its plastic prefilled syringe presentation

  • Lighter while being more resistant as compared with glass syringes
  • Less fragile and more secure as compared with glass syringes
  • Ergonomic and performant pushrod
  • Adaptor and offset wedge compatible

Available in 3 different formats: 10ml, 15ml, 20ml

> Compatible on OptiStar Elite MRI contrast media injector**

Optiray® (loversol) in Prefilled Syringes

With its unique combination of ready-to-use presentation, wide range of concentrations and appropriate physicochemical properties8-11, Optiray® helps you cover a large array of clinical situations, including the challenging ones8,12,13

  • Safe14 and hygienic
  • Quick and easy workflow
  • Exclusive for single-use (one patient) 
  • No glass and no needle

4 different concentrations:
240, 300, 320 and 350 mg I/mL
Available in 50 to 125 mL volumes*

> Compatible on OptiVantage CT contrast media injector**

*Not all presentations may be available in your country. Please check with your local Guerbet representative for more information.

** data on file

Place of prefilled syringes in COVID-19 patient based on current evidence

Ludwin K. et al, Place of prefilled syringes in COVID-19 patient based on current evidence, The American Journal of Emergency Medicine, 2021, Vol 39, p234-235

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Sources & References:

  1. Vogl TJ et al. An observational study to evaluate the efficiency and safety of ioversol pre-filled syringes compared with ioversol bottles in contrast-enhanced examinations. Acta Radiol. 2012: 1-7
  2. Buerke et al, Microbiologic Contamination and Time Efficiency of Use of Automatic MDCT Injectors with Prefilled Syringes: Results of a Clinical Investigation. AJR 2010; 194:299–303
  3. American Society of Radiologic Technologists Education and Research Foundation. Contrast administration safety survey. Albuquerque, NM: American Society of Radiologic Technologists: 2006.
  4. Lafuma A et al. Comparison on the time to prepare contrast media injection in CT scan exam with prefilled syringes and bottles in 7 European countries. Value Health. The Journal of the International Society for Pharmacoeconomics and Outcomes Reasearch. 2009; 12(7):pA254.
  5. Pichler W et al. Hygiene-related considerations for examinations conducted with contrast media. Wiener Klinisches Magazin; March 2009:36-39
  6. APIC. Guide to the elimination of methicillin-resistant Staphylococcus aureus (MRSA) transmission in hospital settings, 2nd edition. 2010
  7. Panella H, et al. Transmission of hepatitis C virus during computed tomography scanning with contrast. Emerg Infect Dis 2008; 14:333-6
  8. SmPC
  9. Le Mignon MM, Azau C, Arthaud A, Bonnemain B. Preliminary European intravenous clinical experience with a new, low osmolar, nonionic contrast medium: ioversol (Optiray®). Eur J Radiol. 1991;13:126-133.
  10. Voeltz MD, et al. The Important Properties of Contrast Media: Focus on Viscosity. J Invasiv Cardiol 2007;19(3):1A-9A.
  11. Bonnemain B, et al. New iodinated, low-osmolar contrast media. Arevised concept of hydrophilicity. Invest Radiol 1990;25(Suppl 1):S104-6.
  12. Azzalini L, et al. Incidence of contrast-induced acute kidney injury in a large cohort of all-comers undergoing percutaneous coronary intervention: Comparison of five contrast media. Int J Cardiol 2018;273:69–73.
  13. Iyengar SS, et al. Diagnostic accuracy of high-definition CT coronary angiography in high-risk patients. Clin Radiol 2016;71:151-158.
  14. Gomi T. et al., Are there any differences in acute adverse reactions among five low-osmolar non-ionic contrast media? Eur. Radiol., 2010; 20: 1631-1635

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P21000428 - March 2021